Phospho-beclin-1
WebMay 26, 2024 · Beclin 1 protects cells from necroptosis in an autophagy-independent manner. Beclin 1 is a modulator of the apoptosis pathway [].To further identify whether Beclin 1 is involved in TNFα-induced ... Web14-3-3ζ binds to and stabilizes phospho-beclin 1 S295 and induces autophagy in hepatocellular carcinoma cells 14-3-3ζ binds to and stabilizes phospho-beclin 1 S295 and induces autophagy in hepatocellular carcinoma cells J Cell Mol Med. 2024 Jan;24 (1):954-964. doi: 10.1111/jcmm.14806. Epub 2024 Nov 11. Authors
Phospho-beclin-1
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WebBeclin-1 has been shown to interact with 14-3-3 proteins through Akt-mediated phosphorylation at Ser234. Beclin 1 pS234 Antibody is ideal for researchers interested in cancer research. Application Note. Anti-Phospho-Ser234 Beclin-1 Antibody is tested for WB. Expect a band at approximately ~60 kDa on specific lysates or tissues. WebThe Beclin-1 S14 phosphorylation by ULK is required for full autophagic induction in mammals and this requirement is conserved in C. elegans. Our study reveals a molecular link from ULK1 to activation of the autophagy specific VPS34 …
WebWestern blot - Phospho-Beclin 1-Ser15 Rabbit pAb (AP1252) Western blot analysis of extracts of various cell lines, using Phospho-Beclin 1-Ser15 antibody (AP1252) at 1:500 dilution.NIH/3T3 and C6 cells were treated by Calyculin A (100 nM) at 37℃ for 30 minutes after serum-starvation overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L ... WebBeclin-1 was purified and immunoblotted as in Fig.3b. (d) Wild-type or ULK def MEF were incubated with or without amino acids. Beclin-1 was purified and immunoblotted as in Fig.3a. Two unique experiments were performed. Article Snippet: Anti-phospho-Beclin-1 (S14) was obtained from Abbiotec, San Diego, CA (Cat#254515).
Web在本研究中，ROT 通过增加 DEPTOR 水平和 p -/t-AMPK 比率。此外，ROT 通过降低 p-/t-ERK1/2 比率和 beclin-1 水平来增加 p-/t-Akt 比率和糖原合酶激酶-3β (GSK3β) 活性。ROT 还通过在 Triton X-100 可溶性和不溶性细胞裂解物部分中诱导自噬体形成来促进 LC3B-I 脂化为 … WebWestern Blot analysis of Phospho-Beclin 1 (Ser90) in various cell lines using a Phospho-Beclin 1 (Ser90) Polyclonal antibody ( Product # PA5-121359) at a dilution of 1:500. 25 µg of lysate or protein were loaded into each lane. A blocking buffer of 3% nonfat dry milk in TBST was used. An HRP conjugated Goat Anti-Rabbit IgG (H+L) secondary ...
WebObjective: Hydrogen sulfide (H 2 S), a gaseous signal molecule, plays a crucial role in many pathophysiologic processes in the cardiovascular system. Autophagy has been shown to participate in the occurrence of many cardiac diseases. Increasing evidences indicated that H 2 S regulates myocardial structure and function in association with the altered …
WebPolyclonal Antibody for studying Beclin 1 (Ser90) phosphate. Cited in 2 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, Phospho-Beclin-1 (Ser90) Antibody (CST #86455) is ready to ship. how did cody bellinger hurt his shoulderWebOct 27, 2024 · These results clearly exhibited that Beclin 1 was phosphorylated at Ser90 and the antibody for phosphorylated Beclin 1 at Ser90 was specific. Ionomycin, EB1089, and Vitamin D3, three... how did coco chanels mum dieWebSep 12, 2013 · Lysates were immunoprecipitated with anti-Beclin 1 followed by western blot analysis with anti-phospho-Beclin 1 Y233. (F) Western blot detection of phospho-Beclin 1 Y233 in NSCLC cell lines with or without active EGFR mutations. Phospho-Beclin 1 Y233 was detected as in (E). See text for information on cell lines. how many seasons of 1923 have been releasedWebSpecificity / Sensitivity. Phospho-Beclin-1 (Ser90) Antibody recognizes endogenous levels of Beclin-1 protein only when phosphorylated at Ser90. The antibody may not react with … how many seasons of 1923WebPhospho-Beclin 1 (Ser234) Antibody (PA5-35393) in WB Western blot analysis of Phospho-Beclin1 pSer234 in flag-beclin-1 wild-type immunoprecipitates expressed in 293T cells … how did cody bellinger get hurtWebBeclin 1 Antibodies Antibodies that detect Beclin 1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and Immunoprecipitation. These antibodies target Beclin 1 in Human, Rat, Mouse, Non-human primate and Canine samples. how did coconuts get to the caribbeanWebFeHV-1 is the causative agent of infectious rhinotracheitis in cats. The relationship between viral infection and the PI3K/Akt/mTOR pathway, as well as its function in crucial physiological processes like as autophagy, apoptosis or the IFN induction cascade is known for other varicelloviruses. how did coding start