Incidence of thrombocytopenia with daptomycin
WebJun 15, 2006 · The use of daptomycin has been associated with an elevation in creatine phosphokinase level, with a reported incidence of 2.8% in phase III clinical trials. Published case reports have documented the presence of myopathy in patients who received daptomycin; however, there have been no previously reported cases of rhabdomyolysis in … WebJun 4, 2024 · The third patient presented unexplained thrombocytopenia; daptomycin and proton-pump inhibitors were stopped, followed by a normalization of platelet values. This observational study of 71 patients with severe infections and co-morbidities adds to the evidence that HDD is effective and well-tolerated in both IE and SWI.
Incidence of thrombocytopenia with daptomycin
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WebJun 1, 2024 · Drug-induced thrombocytopenia (DITP) is an adverse reaction that has been reported with more than 300 medications, most commonly due to drug-dependent platelet antibodies that produce a response from the reticuloendothelial system [1, 2 ]. WebOct 28, 2024 · In 2 recent studies, the prevalence of thrombocytopenia was highly variable, as it ranged from 6% to 24%. 4, 5 Furthermore, follow‐up data about the relationship between thrombocytopenia and mortality in patients with AF were not reported.
WebJul 5, 2024 · Drug-induced non-immune thrombocytopenia. Drugs like valproic acid, daptomycin, linezolid cause thrombocytopenia by dose-dependent suppression of platelet production. Infections: Viral: HIV, hepatitis C, Ebstein-Barr virus, parvovirus, mumps, varicella, rubella, Zika viral infections can cause thrombocytopenia. WebMar 7, 2024 · Daptomycin is a lipopeptide antimicrobial with activity against gram-positive organisms, including antimicrobial-resistant pathogens such as methicillin-resistant …
WebNov 30, 2024 · Thrombocytopenia can occur in 10% to 30% of patients treated with heparin in the absence of an obvious involvement of the immune system. The underlying pathophysiology is thought to be mediated by direct binding of heparin to platelets, resulting in mild platelet activation. WebJun 1, 2024 · In the subset of studies focusing on high-dose daptomycin, patients receiving daptomycin tended to show a higher clinical response rate (OR 1.61; 95% CI 0.37–7.09; I2 …
WebOct 21, 2024 · Citation 148 Weigelt et al found the incidence of reported thrombocytopenia (level not defined) was statistically more common in 592 patients receiving linezolid ... and vancomycin were USD $18,057, $20,698, and $23,671, respectively. The cost-effectiveness ratios for linezolid, daptomycin, and vancomycin were calculated to be $37,604, $44,086 ...
WebFrom 2015 to 2024, the age-adjusted incidence of leukemia in the United States was 14.1 per 100,000 people per year. 1 In the past decade, ... Leukopenia, thrombocytopenia, ... fisher rodenbeck invitationalWeb公開日期 標題 作者 來源出版物 scopus WOS 全文; 1: 2024: A High Daptomycin Dose Is Associated with Better Bacterial Clearance in Infections Caused by Vancomycin-Resistant Enterococcus faecium Regardless of Daptomycin Minimum Inhibitory Concentration in a Rat Infective Endocarditis Model fisher roasted peanuts in the shellWebDec 13, 2014 · Subgroup analysis of studies that reported aORs indicated that daptomycin was associated with higher mortality (OR: 1.59, 95% CI: 1.02–2.50, p = 0.04). There was no evidence of publication bias, but all enrolled studies were retrospective, had small sample sizes, and had substantial limitations. Conclusions fisher rock n playWebNational Center for Biotechnology Information fisher rocker reclinerWebthe patient was initiated on daptomycin 6 mg/kg (300 mg) daily in response to wound cultures detecting Enterococcus faecium susceptible only to daptomycin and linezolid. Starting 96 hours after daptomycin initiation, there was a profound reduction in the patient’s WBC, reaching a nadir of 1.63 x 10-3 /µL after 12 days of therapy. Prior to ... fisher rock freeport ilWebApr 2, 2024 · There was no difference in adverse event incidence between LZD and comparators. These findings suggest that LZD could be a potential first-line drug against MRSA bacteremia as well as VCM or DAP. Keywords: meta-analysis; linezolid; effectiveness; methicillin-resistant Staphylococcus aureus; bacteremia 1. Introduction can a method return an array javaWebApr 12, 2024 · Immune thrombocytopenia (ITP) is the consequence of a complex, still not completely understood immunological dysregulation. Proposed mechanisms include autoantibody-induced platelet destruction, impaired platelet production as well as abnormalities in T-cell immunity, such as Th1 polarization, a high proportion of Th17 cells … fisher roeland attorneys